Myeloproliferative Neoplasias (MPN) | Clinical Medicine

What's up ninja nerds? We got a cool topic to talk about today. It is milo proliferative neoplasia. Like what the heck could that be? There's a lot of different things that we'll discuss in this and again it's going to be more clinical medicine oriented. We'll talk about things like polyythemeia vera essential thrombocythemia. We'll talk a lot about primary myo fibrosis and then a little one on CML but we'll talk about that more chronic leukemas. But again, you may ask, "Hey, Zach, thank you so much for these videos. How can we, you know, support you? " And there is a couple different ways. You could do it by hitting the like button, commenting on the comment section of subscribing. It really goes a long way for us to keep putting these free videos out for you guys' enjoyment. So, please do that. Also, if you get a chance, go in the description box below, click on our link, go to our website. We have lots of cool things that we can offer that's more premium resources. Become a member. Things like notes and illustrations and quiz questions, all those things that helps with space repetition and to know the topic. All right, let's talk a lot about myop proliferative neoplasia. All right, my friends, let's talk about the pathophysiology of myop proliferative neoplasia. So it's basically a concept that we have to understand that when we talk about you know hematopoesis is the production of blood cells, right? And it usually occurs in the bone marrow. So if you take a chunk of the bone marrow and you look there's these stem cells and all that they do is they kind of start off and then they proliferate and they differentiate into specific cell lines. So, for example, in the bone marrow, we could use that stem cell to make a white blood cell. We could use it to make a red cell. We could use it to make a platelet. It's just important to remember that that stem cell is a very specific type. So, we all start off with a basic stem cell. So, if we were to kind of take and zoom in on the bone marrow here, this is called a heo cyto blast. It's basically a pur potent stem cell. And what happens is what it'll do is it will proliferate and differentiate into specific types of blast cells um or stem cells