Acute Leukemia | Clinical Medicine

What's up, Ninja Nerds? In this video today, we're going to be talking about acute leukemias. This is a part of our clinical medicine section. If you guys like these videos, it makes sense to you, please support us. You can do that in a couple different ways, and it really does go a long way. You can hit the like button, you can comment down the comment section, and you can subscribe. Also, we have a website. If you guys go down the description box below, click on that link, it'll take you there. On our website, we have great notes, illustrations, quiz questions, all those things that will help you that go beyond what we talk about sometimes on this lecture and I think it' be good space repetition to help you out for your exams. Go check it out. All right, let's dig in to the pathofizz. All right, so let's begin our discussion on the pathophysiology. So when we talk about acute leukemias, this is basically two different types. One is acute myoid leukemia, AML, and the other one is acute lymphoplastic leukemia or alll. Now when we talk about these, these are really disorders of hematopolesis. So we have to define what that is. So hematopoesis is basically imagine here's your bone marrow right you know the site of uh white blood cell production red blood cell production platelet production all of that's the red bone marrow so we can define hematopoesis as the site of blood cell production and that occurs where in the red bone marrow so for example let's say that I have here a bone in this bone right we'll have some red bone marrow that red bone marrow is the site of where we're going to make all our different types of cells that circulate throughout the blood the white blood cells this can be the granulite and the a granular sites. This could be your red blood cells and this could be your platelets. Question you may have is how do I take this bone marrow and make all these different types of cells? Well, that goes back to your physiology. So, you have to remember inside of the red bone marrow, there's a stem cell. This stem cell is called the hemocytoblast. So, the hemocyblast is basically like a pur potent stem cell which can make all different types of cells. That's what makes it cool. I can make red cells, white cells, platelets, all these different types. What's really cool is that this guy can differentiate.